Under Construction & Updates - January 2025
We are adding new information on specific topics - weekly . Thank you for your interest!
Technical Workflows and Applications
Applied Omics and Life Sciences LLC delivers technical and business expertise related to LC MS based technologies and associated testing workflows for bioanalytical needs. The expertise extends to applications in biomedical research, bioanalytical pipelines, clinical research, and new method / technology developments.
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Technical and Workflow Expertise
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Whether it be proteomics or metabolomics – or small molecule clinical research panels, Applied Omics and Life Sciences LLC has expertise in development and implementation of LC MS based workflows for many types of research. Jeremiah Tipton, Ph.D., has been developing and implementing LC MS based methods for 20+ years across multiple markets and research fields.
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General List of Workflows ​
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Examples Below are based on Molecules of interest.
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Sample: Example is Plasma
** Implement existing (or new) methods for sample preparation base on molecule(s) of interest, volume, etc.
Sample Preparation - Microsamples - Automations
** Method used is dependent on the molecular system of interest and the source of the sample.
Implement New or Existing LC MS Assay for Testing Specific Small Molecules
Example:Amino Acids
Example: Environmental - pfas
Example: Hormones and Steroids
Sample: Example is Plasma
** Several standard proteomics workflows have been developed for a variety of sample types.
Sample Preparation - Microsamples - Automations
** Method used is dependent on the experiment type, results needed,
and the source of the sample.
Implement New or Existing LC MS Assay for Testing Specific Proteomic Studies
Mechanism of Action &
Pathway Analysis
Targeted - High Throughput
Fit-for-Purpose Peptide Analysis Assays
Example Proteomics Assay
Epiproteomics
Sample: Example is Plasma
** Several standard metabolomics workflows have been developed for a variety of sample types.
Sample Preparation - Microsamples - Automations
** Method used is dependent on the molecular system of interest and the source of the sample.
Implement New or Exiting LC MS Assay for Testing Specific Metabolomics Studies
Example: Metabolism & Metabolic Pathways - Semi Targeted
High-Throughput - Targeted
Fit-for-Purpose Analysis Assays
Example: Comparative
Discovery Metabolomics
Samples - Example - Antibody Analysis
** Biologics, Biosimilars, Host-Cell Protein Analysis,
Chemoproteomics, etc.
Sample Preparation - Microsamples - Automations
** Method used is dependent on the molecular system of interest and the source of the sample.
Implement New or Existing LC MS Assay for Testing Specific Large Molecule Analysis
Example: Antibody Structure
Characterization
High-Throughput - Targeted
Quality Control - Host Cell Proteins
Example: Enzyme Kinetics
Ligand Binding Assays
